Hyo-Jung Lee Selected Research

Prostaglandins G

1/2022	Apoptotic and DNA Damage Effect of 1,2,3,4,6-Penta-O-galloyl-beta-D-glucose in Cisplatin-Resistant Non-Small Lung Cancer Cells via Phosphorylation of H2AX, CHK2 and p53.
8/2012	Reactive oxygen species-mediated activation of JNK and down-regulation of DAXX are critically involved in penta-O-galloyl-beta-d-glucose-induced apoptosis in chronic myeloid leukemia K562 cells.
3/2012	Penta-O-galloyl-β-D-glucose attenuates cisplatin-induced nephrotoxicity via reactive oxygen species reduction in renal epithelial cells and enhances antitumor activity in Caki-2 renal cancer cells.
8/2011	The genome-wide expression profile of 1,2,3,4,6-penta-O-galloyl-β-D-glucose-treated MDA-MB-231 breast cancer cells: molecular target on cancer metabolism.
6/2011	Oral administration of penta-O-galloyl-β-D-glucose suppresses triple-negative breast cancer xenograft growth and metastasis in strong association with JAK1-STAT3 inhibition.
3/2011	1,2,3,4,6-Penta-O-galloyl-beta-D-glucose reduces renal crystallization and oxidative stress in a hyperoxaluric rat model.
1/2010	1,2,3,4,6-Penta-O-galloly-beta-D-glucose suppresses hypoxia-induced accumulation of hypoxia-inducible factor-1α and signaling in LNCaP prostate cancer cells.

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Hyo-Jung Lee Research Topics

Disease

63	Neoplasms (Cancer) 11/2022 - 01/2005
14	Prostatic Neoplasms (Prostate Cancer) 07/2022 - 01/2006
8	B-Cell Lymphoma (Lymphoma, B Cell) 01/2022 - 09/2017
8	Neoplasm Metastasis (Metastasis) 08/2021 - 01/2005
7	Lung Neoplasms (Lung Cancer) 01/2022 - 10/2006
7	Lewis Lung Carcinoma 10/2009 - 10/2006
6	Pain (Aches) 04/2021 - 01/2009
6	Breast Neoplasms (Breast Cancer) 11/2018 - 01/2007
6	Hypoxia (Hypoxemia) 08/2011 - 06/2007
5	Body Weight (Weight, Body) 06/2022 - 10/2006
5	Hepatocellular Carcinoma (Hepatoma) 06/2022 - 09/2017
5	Colorectal Neoplasms (Colorectal Cancer) 12/2021 - 01/2013
5	Colonic Neoplasms (Colon Cancer) 08/2021 - 03/2009
4	Liver Neoplasms (Liver Cancer) 09/2021 - 08/2012
4	Inflammation (Inflammations) 01/2021 - 11/2006
4	Obesity 05/2017 - 08/2008
4	Carcinogenesis 11/2015 - 03/2007
4	Multiple Myeloma 03/2014 - 06/2011
4	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 01/2013 - 07/2011
4	Fibrosarcoma 01/2011 - 07/2009
3	Periodontitis 12/2021 - 06/2015
3	Uterine Cervical Neoplasms (Cancer of the Cervix) 08/2021 - 01/2017
3	Hyperalgesia 02/2018 - 01/2009
3	Kidney Calculi (Kidney Stone) 01/2013 - 03/2011
3	Leukemia 08/2012 - 12/2010
3	Myeloid Leukemia (Leukemia, Myelocytic) 07/2011 - 09/2008
2	Periodontal Diseases (Periodontal Disease) 12/2021 - 01/2019
2	Hemorrhage 12/2021 - 10/2017
2	Edema (Dropsy) 04/2021 - 04/2012
2	Fatty Liver 01/2019 - 05/2017
2	Hyperlipidemias (Hyperlipidemia) 01/2019 - 09/2012
2	Cardiovascular Diseases (Cardiovascular Disease) 01/2019 - 03/2008

Drug/Important Bio-Agent (IBA)

18	Proteins (Proteins, Gene)FDA Link 01/2022 - 01/2005
11	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 11/2017 - 06/2007
10	Caspase 3 (Caspase-3)IBA 12/2021 - 10/2006
8	CaspasesIBA 01/2022 - 10/2006
8	Pharmaceutical PreparationsIBA 10/2020 - 02/2010
7	Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA 01/2022 - 09/2017
7	Prostaglandins GIBA 01/2022 - 01/2010
7	AntioxidantsIBA 09/2021 - 01/2010
6	Cisplatin (Platino)FDA LinkGeneric 01/2022 - 03/2009
6	decursinIBA 01/2013 - 01/2006
5	Androgen Receptors (Androgen Receptor)IBA 07/2022 - 01/2006
5	DNA Nucleotidylexotransferase (Terminal Deoxynucleotidyl Transferase)IBA 01/2022 - 12/2006
5	AntigensIBA 01/2022 - 03/2011
5	MelatoninIBA 08/2021 - 05/2011
5	ginsenoside M1IBA 08/2021 - 01/2010
5	SaponinsIBA 08/2021 - 01/2010
5	Phosphotransferases (Kinase)IBA 01/2020 - 05/2011
5	AMP-Activated Protein KinasesIBA 01/2020 - 01/2013
5	Messenger RNA (mRNA)IBA 03/2011 - 06/2007
4	Biomarkers (Surrogate Marker)IBA 11/2022 - 01/2011
4	Small Interfering RNA (siRNA)IBA 01/2022 - 01/2011
4	X-Linked Inhibitor of Apoptosis ProteinIBA 01/2022 - 09/2018
4	Reactive Oxygen Species (Oxygen Radicals)IBA 09/2017 - 03/2012
4	Ethanol (Ethyl Alcohol)IBA 05/2017 - 01/2006
4	AndrogensIBA 01/2011 - 01/2006
3	LigandsIBA 11/2022 - 03/2007
3	CateninsIBA 07/2022 - 09/2018
3	STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA 06/2022 - 06/2011
3	SurvivinIBA 01/2022 - 12/2010
3	pentagalloylglucoseIBA 01/2022 - 06/2011
3	NF-kappa B (NF-kB)IBA 08/2021 - 11/2006
3	Cysteine (L-Cysteine)FDA Link 02/2021 - 09/2018
3	Peptide Hydrolases (Proteases)FDA Link 02/2021 - 09/2018
3	lambertianic acidIBA 02/2021 - 09/2017
3	Peptides (Polypeptides)IBA 12/2020 - 01/2009
3	Biological ProductsIBA 12/2019 - 08/2011
3	Transcription Factors (Transcription Factor)IBA 12/2019 - 01/2010
3	EnzymesIBA 05/2017 - 01/2010
3	Matrix Metalloproteinases (MMPs)IBA 06/2015 - 07/2009
3	CytokinesIBA 06/2015 - 11/2006
3	JNK Mitogen-Activated Protein KinasesIBA 03/2014 - 08/2012
3	ResveratrolIBA 01/2013 - 10/2006
3	PENTAIBA 08/2012 - 06/2011
3	p38 Mitogen-Activated Protein KinasesIBA 02/2011 - 08/2008
3	Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA 10/2009 - 12/2006
2	Immune Checkpoint InhibitorsIBA 11/2022 - 01/2022
2	Prostate-Specific Antigen (Semenogelase)IBA 07/2022 - 07/2009
2	cinnamaldehyde (cinnamic aldehyde)FDA Link 06/2022 - 01/2013
2	TensinsIBA 01/2022 - 01/2010
2	Complement System Proteins (Complement)IBA 01/2022 - 02/2010
2	Hyaluronic Acid (Hyaluronan)IBA 01/2022 - 12/2017
2	Calcibiotic Root Canal SealerIBA 12/2021 - 10/2019
2	morusinIBA 12/2021 - 09/2021
2	Protein Kinases (Protein Kinase)IBA 08/2021 - 05/2017
2	TOR Serine-Threonine KinasesIBA 07/2021 - 09/2017
2	PhytochemicalsIBA 03/2021 - 01/2011
2	ribosomal protein L5IBA 02/2021 - 01/2020
2	Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA 01/2021 - 11/2015
2	Mid1ip1IBA 01/2020 - 01/2019
2	Cyclin D1IBA 09/2018 - 01/2018
2	Paclitaxel (Taxol)FDA LinkGeneric 09/2018 - 08/2011
2	Histones (Histone)IBA 09/2018 - 03/2012
2	Acetyl-CoA CarboxylaseIBA 09/2018 - 09/2017

Therapy/Procedure

18	Therapeutics 11/2022 - 01/2010
11	Immunotherapy 11/2022 - 06/2015
7	Traditional Medicine (Folk Remedies) 05/2017 - 03/2008
4	Chemoprevention 06/2007 - 01/2006
3	Drug Therapy (Chemotherapy) 01/2018 - 08/2011